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metabase-representation-formatmetabaseUnderstands the Metabase Representation Format — a YAML-based serialization format for Metabase content (collections, cards, dashboards, documents, segments, measures, snippets, transforms). Use when the user needs to create, edit, understand, or validate Metabase representation YAML files, or when working with Metabase serialization/deserialization (serdes). Covers entity schemas, MBQL and native queries, visualization settings, parameters, and folder structure.metabase-semantic-checkermetabaseRuns the Metabase semantic checker against a tree of Representation Format YAML files to verify that all references resolve — cross-entity references (collection_id, dashboard_id, parent_id, parameter source cards, snippet references, transform tags, etc.) and references to columns inside MBQL and native queries. Slow (≥1 min per run). Only use when the user explicitly asks to verify entity references or column references in MBQL/SQL queries; in most cases this runs as a CI step, not locally. Remetamask-agent-walletmetamaskUse when the user asks anything about blockchain wallets, transactions, signing, token transfers, supported chains, wallet balances, perpetual futures trading, prediction markets, token swaps, cross-chain bridges, market data, token discovery, decoding EVM calldata, DeFi earn/yield vaults, installing or removing third-party `mm` CLI plugins, or authentication via the MetaMask Agentic CLI; also when an HTTP request returns 402 Payment Required / x402, when an MCP tool call returns an x402 paymentarchitecture-diagram-creatormhattingpeteCreate comprehensive HTML architecture diagrams showing data flows, business objectives, features, technical architecture, and deployment. Use when users request system architecture, project documentation, high-level overviews, or technical specifications.codebase-documentermhattingpeteGenerates comprehensive documentation explaining how a codebase works, including architecture, key components, data flow, and development guidelines. Use when user wants to understand unfamiliar code, create onboarding docs, document architecture, or explain how the system works.file-operationsmhattingpeteAnalyze files and get detailed metadata including size, line counts, modification times, and content statistics. Use when users request file information, statistics, or analysis without modifying files.flowchart-creatormhattingpeteCreate HTML flowcharts and process diagrams with decision trees, color-coded stages, arrows, and swimlanes. Use when users request flowcharts, process diagrams, workflow visualizations, or decision trees.blast-radiusmichael-denyerFind what a change could break somewhere else before it ships, beyond the diff, and prove the one fact it's safe because of by running real code instead of writing it up. Use for 'blast radius of X', 'what could this break', reviewing a small diff you don't trust, or a brief that asserts something about existing code ('make X public', 'X already handles Y') before you design against that assertion.deslopmichael-denyerRemove AI-generated code slop and clean up code stylehowmichael-denyerUse for \"how does X work\", code walkthroughs before changing something, and placement / ownership / layering questions (\"where should this live\", \"which package owns this\", \"is this the right layer\"). Explains subsystem architecture, runtime flow, onboarding mental models. Use why for motivation.poteto-modemichael-denyerpoteto's agent style for concise, detailed responses, deliberate subagents, unslopped prose, simple code, and verified work. Use for poteto, /poteto-mode, or requests to work in this style.unslopmichael-denyerCut AI tells from any writing. Must always apply.article-extractormichalparkolaExtract clean article content from URLs (blog posts, articles, tutorials) and save as readable text. Use when user wants to download, extract, or save an article/blog post from a URL without ads, navigation, or clutter.youtube-transcriptmichalparkolaDownload YouTube video transcripts when user provides a YouTube URL or asks to download/get/fetch a transcript from YouTube. Also use when user wants to transcribe or get captions/subtitles from a YouTube video.aspiremicrosoft**WORKFLOW SKILL** - Aspire router. Detects AppHosts, enforces guardrails, and selects the right sub-skill. USE FOR: Aspire AppHost, Aspire CLI, distributed app, cloud-native .NET, aspire start/stop/resource/deploy/destroy/publish/init/new/add/wait/describe/ps/logs/otel, aspire agent init, WithBrowserLogs, WithTerminal, Interaction Service, apphost.mts, TS package managers, Yarn Classic, custom resource commands, .aspire/modules recovery, ProjectResource to DotnetProjectResource migration, or Plaspire-monitoringmicrosoft**ANALYSIS SKILL** - Observe Aspire apps: logs, traces, metrics, resource state, telemetry export, browser telemetry, and the standalone dashboard. Routes between local Aspire CLI, AKS workload diagnostics, and deployed Azure resource health. USE FOR: aspire logs, aspire otel logs, aspire otel traces, aspire otel spans, aspire describe, aspire ps, aspire export, aspire dashboard run, describe --include-hidden, browser logs in dashboard, terminal view, DevTunnel URLs, WithBrowserLogs, App Insightaspire-orchestrationmicrosoft**WORKFLOW SKILL** — Manage Aspire lifecycle in VS Code or the CLI. WHEN: "start or stop my Aspire app", "aspire_apphost_start", "aspire_apphost_stop", "notEditorOwned", "ambiguousSession", "aspire start", "aspire stop", "aspire wait", resource restart, file-lock errors (MSB3491 or CS2012), port conflicts, git worktrees, "--isolated", "aspire update --self", "aspire update --migrate", "aspire describe --include-hidden", "aspire stop --force", "aspire terminal", integration discovery, default watazure-kusto-graphmicrosoftBuild and query Kusto graphs from natural language. Covers transient graphs (make-graph), persistent graph models/snapshots, pattern matching (graph-match), shortest paths, connected components, and graph-to-table export. Generates the edges-first thinking: define edges, define node lookups, union, make-graph. WHEN: make-graph, graph-match, graph-shortest-paths, graph-to-table, graph-mark-components, persistent graph, graph model, graph snapshot, build a graph from data, find paths between nodesazure-kusto-irqlmicrosoftCompose IRQL (Incident Response Query Language) queries for Kusto cybersecurity investigations. Translates natural language hunting questions into composable IRQL pipelines using Get_*, Extract_*, and Enrich_* functions. WHEN: IRQL query, security hunt, threat hunting KQL, incident response query, compose hunting pipeline, failed logins, phishing investigation, lateral movement, process execution, file creation events.azure-kusto-irql-graphmicrosoftApply IRQL graph functions to KQL or IRQL query results for Kusto Explorer visualization. Generates Lift_To_Graph mappings and composes Graph_Render_View, Graph_Fold_By_Property, Extract_Node_*, Enrich_Node_*, and Enrich_Graph_* calls. Accepts a supplied query or limited basic natural-language source request; it is not a general natural-language-to-KQL/IRQL skill. WHEN: Lift_To_Graph, Graph_Render_View, Graph_Fold_By_Property, IRQL graph enrichment, graph mapping for existing query results, iconowasp-top-10microsoftOWASP Top 10 for Web Applications (2025) knowledge base for identifying, assessing, and remediating web application security risks.playwright-climicrosoftAutomate browser interactions, test web pages and work with Playwright tests.playwright-devopsmicrosoftDevOps workflows for Playwright - CI failure analysis, workflow debugging, and release operations.azure-container-appsmicrosoftdocsExpert knowledge for Azure Container Apps development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when configuring ACA auth/egress, KEDA/Dapr scaling, CI/CD deployments, Java microservices, or quotas, and other Azure Container Apps related development tasks. Not for Azure App Service (use azure-app-service), Azure Functions (use azure-functions), Azure Kubazure-sql-databasemicrosoftdocsExpert knowledge for Azure SQL Database development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when choosing tiers (DTU/vCore/serverless), configuring geo-replication/DR, Hyperscale, Data Sync, or elastic pools, and other Azure SQL Database related development tasks. Not for Azure SQL Managed Instance (use azure-sql-managed-instance), SQL Server on Azure azure-well-architectedmicrosoftdocsExpert guidance for designing, assessing, and optimizing Azure workloads using Azure Well Architected. Covers design review checklists, recommendations, design principles, tradeoffs, service guides, workload patterns, and assessment questions. Use when designing AI, HPC, SaaS, AVD, or mission-critical workloads and optimizing Azure services by WAF pillars, and other Azure Well Architected related development tasks.microsoft-code-referencemicrosoftdocsFind working code samples, verify API signatures, and fix Microsoft SDK errors using official docs. Use whenever the user is writing, debugging, or reviewing code that touches any Microsoft SDK, .NET library, Azure client library, or Microsoft API—even if they don't ask for a "reference." Catches hallucinated methods, wrong signatures, and deprecated patterns. If the task involves producing or fixing Microsoft-related code, this is the right skill.microsoft-docsmicrosoftdocsUnderstand Microsoft technologies by querying official documentation. Use whenever the user asks how something works, wants tutorials, needs configuration options, limits, quotas, or best practices for any Microsoft technology (Azure, .NET, M365, Windows, Power Platform, etc.)—even if they don't mention "docs." If the question is about understanding a concept rather than writing code, this is the right skill.microsoft-skill-creatormicrosoftdocsCreate agent skills for Microsoft technologies using official documentation. Use whenever the user wants to build, generate, or scaffold a skill for any Microsoft technology (Azure, .NET, M365, VS Code, Bicep, etc.)—even phrased casually like "make a skill for Cosmos DB." Investigates the topic via official docs, then generates a hybrid skill with essential knowledge stored locally and dynamic lookups for depth.conversion-psychologymike-coulbournUse when optimizing sponsored or affiliate video scripts to convert, diagnosing why content is not driving action, or choosing which persuasion lever fits an offer. Keywords - buyer psychology, emotional triggers, social proof, scarcity, urgency, authority, reciprocity, loss aversion, why people buy.code-qualitymiles990Clean code principles, SOLID, and code review practicesdevops-cicdmiles990CI/CD pipelines, infrastructure as code, and deployment strategiesdeslopmillioncoSimplify and refine recently modified code while preserving functionality. Use when asked to "deslop", "clean up code", "simplify code", or after making changes that could benefit from refinement.setup-tooluniversemims-harvardInstall and configure ToolUniverse for any use case — MCP server (chat-based), CLI (command line with 14 subcommands), or Python SDK (Coding API with 3 calling patterns). Covers uv/uvx setup, MCP configuration for 12+ AI clients (Cursor, Claude Desktop, Windsurf, VS Code, Codex, Gemini CLI, Trae, Cline, etc.), full CLI reference (tu list/grep/info/find/run/test/status/build/remote/doctor/serve/connect/connections/disconnect), Coding API quickstart, agentic tools, code executor, API key walkthroutooluniversemims-harvardToolUniverse plugin router. STEP 1 BEFORE ANY ANALYSIS: if the data folder contains `*_executed.ipynb`, run `tu run read_executed_notebook '{\"data_folder\":\"<path>\",\"search\":\"<keyword>\"}'` to extract its cell outputs and apply EVERY filter/sample-exclusion the notebook used — even when the question says 'Using DESeq2/Run X/Compute Y' (this describes the METHOD the notebook used, not a request to rerun). The notebook's cell outputs are the only published authoritative answers; reimplementitooluniverse-chemical-compound-retrievalmims-harvardRetrieve chemical compound data from PubChem and ChEMBL with disambiguation, cross-referencing, and stereochemistry handling. Use for resolving compound names to SMILES/InChI/CID/ChEMBL IDs (including OPSIN deterministic IUPAC-name-to-structure parsing), fetching molecular properties, distinguishing isomers/stereo forms, and cross-validating identity across databases. Always use English compound names; flags ambiguous queries (e.g., Vitamin D has multiple forms).tooluniverse-clinical-guidelinesmims-harvardSearch and retrieve clinical practice guidelines from 12+ authoritative sources — NICE, WHO, NCCN, AHA, ADA, SIGN, USPSTF, IDSA, NIH consensus, ESMO/ESC/EASL European societies, and US specialty associations. Use for evidence-graded treatment recommendations, dosing protocols, screening guidance, and authoritative-source-prioritized clinical guidance (NICE/WHO ranked above society guidelines).tooluniverse-clinical-trial-designmims-harvardStrategic clinical trial design feasibility assessment. Analyzes 6 dimensions (endpoint, population, comparator, effect size, duration, regulatory pathway) using precedent trials and FDA guidance. Produces enrollment projections, endpoint recommendations, and approval-pathway analysis. Use for trial-protocol design, power/sample-size estimation, comparator selection, and FDA submission strategy. Driven by precedent-based reasoning rather than first-principles math.tooluniverse-disease-researchmims-harvardGenerate comprehensive disease research reports covering genetics (causal genes, GWAS, OMIM), pathways (Reactome, KEGG), drugs (existing therapies, repurposing candidates), clinical trials, epidemiology (prevalence, incidence), and phenotypes (HPO). Use for full disease overviews, comprehensive disease characterization, and orphan/rare-disease profiling.tooluniverse-drug-drug-interactionmims-harvardAssess drug-drug interactions — CYP metabolic interactions (substrate/inhibitor/inducer), transporter (P-gp, BCRP, OATP) effects, pharmacodynamic synergy/antagonism, clinical significance scoring, and management recommendations. Use for polypharmacy review, prescribing decision support, and safety analysis when adding or switching drugs.tooluniverse-drug-researchmims-harvardComprehensive drug profiling — mechanism, primary/secondary targets, drug interactions, clinical-trial status, adverse events (FAERS), pharmacogenomics, and approval history. Use for full drug investigation reports, 'tell me about drug X' queries, and assembling drug profiles for clinicians, researchers, or regulatory work.tooluniverse-epigenomicsmims-harvardGenomics and epigenomics analysis: DNA methylation (CpG, 5mC, 5hmC, bisulfite, RRBS), m6A RNA modification (MeRIP-seq), ChIP-seq peaks, ATAC-seq accessibility, histone modifications, chromatin state, multi-omics integration. Combines pandas/scipy/pysam computation with ToolUniverse annotation tools. Use for genome-wide epigenomic statistics, methylation analysis, and chromatin-genome integration.tooluniverse-image-analysismims-harvardMicroscopy and quantitative imaging analysis — colony morphometry, fluorescence intensity quantification, cell-count statistics, dose-response curves, and ANOVA/Dunnett on image-derived measurements. Uses pandas/numpy/scipy/scikit-image. Use for analyzing tabular outputs from CellProfiler/ImageJ, image-derived measurement statistics, and image-based assay quantification.tooluniverse-literature-deep-researchmims-harvardDeep literature review — PubMed, EuropePMC, bioRxiv preprints, citation networks, evidence synthesis. Disambiguates queries, runs collision-aware searches, grades evidence T1-T4, and produces structured reports. Use for systematic literature review, meta-analysis evidence collection, and detailed answer-with-citations workflows.tooluniverse-network-pharmacologymims-harvardCompound-target-disease network construction and analysis for drug repurposing, polypharmacology discovery, and multi-target drug design. Uses STRING, BioGRID, ChEMBL, DGIdb, OMIM, OpenTargets. Use for off-target effect prediction, network-based drug repurposing, and identifying molecules with desired multi-target profile.tooluniverse-pharmacovigilancemims-harvardDrug safety and adverse event analysis — FAERS spontaneous-report mining, FDA black-box warnings, signal detection (PRR, ROR, IC), risk factors by demographic/comorbidity, and label change tracking. Use for post-market safety surveillance, AE signal investigation, drug-AE association strength scoring, and pharmacovigilance reports.tooluniverse-precision-oncologymims-harvardCancer treatment recommendations from molecular profile (mutations + cancer type + biomarkers) — FDA-approved + investigational therapies, resistance mechanisms, matching clinical trials, prognosis. Uses CIViC, ClinVar, OpenTargets, ClinicalTrials.gov. Use for tumor-board treatment recommendations, evidence-tiered actionability assessment, and FDA-precedent-driven therapy selection.tooluniverse-protein-structure-retrievalmims-harvardProtein structure retrieval from RCSB PDB, PDBe, and AlphaFold with disambiguation, quality assessment (resolution, R-factor, pLDDT), and metadata. Distinguishes high-quality experimental (X-ray under 2 Angstrom) vs predicted vs medium-quality structures. Use for fetching protein structures, structure-quality comparison, and selecting structures for drug design or modeling.tooluniverse-systems-biologymims-harvardSystems biology and pathway analysis integrating Reactome, KEGG, WikiPathways, BioCarta, NCI-Nature Pathway Interaction Database. Multi-database pathway enrichment, protein-pathway relationships, network reasoning. Use for pathway analysis on a gene list, multi-source pathway concordance, and systems-level interpretation across databases.analytics-data-analysismindrallyBest practices for analytics, data analysis, and visualization using Python, pandas, matplotlib, seaborn, and Jupyter notebooks. Use when performing exploratory data analysis, building data pipelines, creating statistical visualizations, writing Jupyter notebooks, cleaning and transforming datasets, or implementing analytics dashboards.

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