Skills
18,283 skills, most installed first.
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bulk-rnaseqk-dense-aiEnd-to-end bulk RNA-seq orchestrator — takes raw FASTQ reads through QC and trimming (FastQC, fastp/Trim Galore), alignment and quantification (STAR, Salmon, featureCounts), assembles a gene-level counts matrix, then hands off to differential expression (pydeseq2), pathway/GSEA enrichment (pathway-enrichment), and publication figures (scientific-visualization). Use whenever the user has bulk RNA-seq reads or quant output and wants a complete, reproducible differential-expression workflow — e.g. deepspot-mk-dense-aiGenerate transcriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. Use when you need spatial gene expression in log1p-CPM for 224x224 tiles at about 20x, want to query protein-coding genes by symbol instead of a fixed panel, or want to run prediction across a whole slide after tiling with histolab.experimental-designk-dense-aiDesign experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable. Use whenever someone is planning a study, asks how to assign subjects/samples to groups, mentions randomization, blocking, stratification, controls, factorial or fractional-factorial designs, design of experiments (DOE), screening many factors, response-surface optimization, crossover or repeated-measures or split-plot designs, clgenomic-coordinatesk-dense-aiConvert genomic intervals between coordinate conventions, normalise and compare variant representations, and detect assembly or contig-naming mismatches before they corrupt an analysis. Use whenever coordinates cross a format, tool, or assembly boundary - converting between BED, GFF/GTF, VCF, SAM/BAM, WIG, PSL, genePred, Picard interval_list, or region strings; reconciling 0-based half-open with 1-based inclusive; left-aligning or trimming indels; checking whether two variant records describe thgenomic-intelligencek-dense-aiPredict regulatory features, gene structure, and expression directly from DNA sequence using Genomic Intelligence's hosted transformer DNA language models — no local GPU or model weights. Six tasks over a REST API and a hosted MCP server (keyless public demo): promoter regions, splice donor/acceptor sites, enhancer activity, chromatin state, sequence-to-expression (log TPM), and de-novo gene annotation, plus a composite find-genes-then-predict-expression workflow. Use when the user has a gene syiso-standards-readinessk-dense-aiPrepares and structurally reviews readiness evidence for ISO management-system and laboratory-competence standards - ISO 13485 medical device QMS, ISO 14971 device risk management, ISO/IEC 17025 testing and calibration laboratories, and ISO 15189 medical laboratories. Use when organizing declared scope, controlled documents, risk-management files, scope of accreditation, traceability, CAPA, external-provider controls, or bounded local evidence manifests, and when separating ISO certification frolab-hardware-cadk-dense-aiDesign custom laboratory hardware as parametric build123d models and export fabrication-ready STEP, STL, and DXF files - microfluidic chips and molds, optomechanical mounts and breadboard adapters, cuvette and microplate holders, tube racks, animal-behavior rigs, and 3D-printed instrument fixtures. Use when a research task needs a physical part that must mate with standardized labware, an optical table, a cage system, or a printer, CNC, or laser process.liteparsek-dense-aiLocal document and PDF parsing that returns spatial text with bounding boxes. Use for extracting text from PDFs, DOCX, Office files, and images; running OCR on scans; producing layout-preserved JSON for RAG; batch-ingesting folders of papers; or rendering pages to PNG for multimodal agents. Distinguishing capabilities are per-token bounding boxes, page raster output, and fully local processing with no cloud API.ncats-araxk-dense-aiQueries the NCATS Translator ARAX production API for bounded, typed, provenance-rich one-hop and endpoint-pinned two-hop biomedical knowledge-graph relationships. Use for Biolink-constrained RTX-KG2 lookup, explicit selected-provider ARAX federation, separate entity normalization, qualifier-aware graph traversal, and inspection of TRAPI edge bindings, publications, and knowledge-source provenance. Do not use for inference, ranking, open-ended pathfinding, clinical guidance, or sensitive queries.nextflowk-dense-aiBuild, run, and debug Nextflow data pipelines and nf-core workflows end to end. Use whenever the user mentions Nextflow, nf-core, .nf files, nextflow.config, DSL2, processes/channels/operators, samplesheets, or wants to run a community pipeline (e.g. nf-core/rnaseq, nf-core/sarek), write or test a module/subworkflow with nf-test, configure executors/containers (Docker, Singularity/Apptainer, Conda, Wave), scale a workflow to HPC/SLURM or cloud (AWS Batch, Google Batch, Azure, Kubernetes), or debonekgpdk-dense-aiQuery the 1000 Genomes Project dataset (3,202 whole-genome-sequenced individuals, GRCh38) at the level of individual participants. Use when a question is about individuals or variants in the 1000 Genomes Project cohort: which individuals carry variants matching specific criteria in a gene or region, which individuals are homozygous-reference at a position, which variants exist in the dataset or carried by specified individuals in a gene or region, the relatedness between two specified individualontology-term-resolutionk-dense-aiResolve free-text scientific labels to ontology term IDs and validate existing CURIEs against the EBI Ontology Lookup Service (OLS4). Also look up prefixes in Bioregistry, resolve compact identifiers via Identifiers.org, map lab shorthand with ZOOMA, and build Ontobee term pages. Use whenever an ontology identifier must be produced or checked - annotating tissue, cell type, disease, phenotype, assay, chemical, organism, sex, or developmental stage fields; preparing metadata for GEO, ENA, BioSampopenpivk-dense-aiParticle Image Velocimetry (PIV) analysis with OpenPIV. Use when extracting velocity fields from PIV image pairs, analyzing fluid dynamics or flow visualization experiments, cross-correlating interrogation windows, validating and replacing spurious PIV vectors, or computing vorticity, strain rate, and turbulence statistics from measured velocity fields.pacsomatick-dense-aiOperator toolkit for nf-core/pacsomatic matched tumor-normal workflows from BAM inputs. Use this skill when the user needs to validate run inputs, generate pacsomatic-compliant samplesheets, prepare reproducible Nextflow launch artifacts, run locally or submit to schedulers (LSF/Slurm/PBS/SGE), and triage execution failures. Triggers on requests to run pacsomatic, prepare launch commands/scripts, perform dry-run checks, or troubleshoot pipeline startup and scheduler submission errors.paperclipk-dense-aiSearch and read full-text biomedical papers, FDA/PMDA/EMA regulatory documents, clinical trial registries, and UniProt/PDB/ChEMBL entries with the Paperclip CLI from GXL. Covers installing and authenticating the `paperclip` binary with a PAPERCLIP_API_KEY, the read-only virtual filesystem under /papers, /fda, /trials, /proteins and /clipboard, source-scoped semantic search, corpus-wide grep, metadata lookup and SQL, map/reduce reading across many papers, figure vision analysis, opt-in paper repopathogen-variant-surveillancek-dense-aiQuery live pathogen genomic surveillance data through the GenSpectrum LAPIS API to find which viral lineages are circulating now, how fast they are growing, and what mutations they carry. Use whenever a question depends on the current state of a pathogen population rather than on remembered facts - which SARS-CoV-2 variant is dominant, whether a Pango lineage is still designated or has been withdrawn, what clade or genotype of H5N1 is in a host or region, whether a PCR primer or assay target stipathway-enrichmentk-dense-aiRun pathway and gene-set enrichment analysis on gene lists or ranked gene data, then interpret the results. Use whenever the user has a set of genes (differentially expressed genes from PyDESeq2/Scanpy, CRISPR-screen hits, cluster marker genes, proteomics hits) and wants to know which biological pathways, GO terms, or gene sets are over-represented or enriched. Covers over-representation analysis (ORA / Enrichr / Fisher / hypergeometric), ranked Gene Set Enrichment Analysis (GSEA / preranked), spi-agentk-dense-aiBuild with and use Pi, the minimal terminal coding harness. Use for installing Pi, configuring providers/models/settings/environment variables, creating Pi skills/extensions/packages/themes/prompt templates, embedding Pi through the SDK, integrating over RPC or JSON event streams, parsing sessions, running local models through the llama.cpp router, developing custom Pi providers and TUI components, or using ecosystem packages such as pi-subagents (delegation/orchestration), pi-mcp-adapter (MCP spkpd-modelingk-dense-aiPharmacokinetic and pharmacodynamic modelling and simulation - non-compartmental analysis, compartmental and population PK, PK/PD and exposure-response, TMDD, PBPK orientation, bioequivalence, allometric scaling and first-in-human dose, drug interaction prediction, and Bayesian therapeutic drug monitoring. Use when analysing concentration-time data, deriving exposure metrics, fitting PK or PD models, or evaluating dosing regimens. Triggers include "pharmacokinetics", "pharmacodynamics", "PK/PD",relsa-severity-assessmentk-dense-aiMultivariate severity assessment and humane endpoint prediction for laboratory animal studies using the RELSA (RELative Severity Assessment) score and ARIMA-based foRcast forecasting. Use when combining welfare readouts — body weight or weight loss, body temperature, clinical or nesting scores, biomarkers, activity, heart rate, burrowing, wheel running — into one severity score per animal per day, when asking which animals are at risk of reaching a humane endpoint or when one will be reached, whstatistical-powerk-dense-aiSample-size and statistical power calculations for planning studies. Use whenever someone asks "how many subjects/samples/replicates do I need", wants an a priori power analysis, a minimum detectable effect (MDE), a power curve, or needs to justify a sample size for a grant, IRB protocol, or pre-registration. Covers closed-form power for t-tests, ANOVA, proportions, correlations, chi-square, and regression, plus simulation-based (Monte Carlo) power for designs with no formula — logistic/Poisson tamarindk-dense-aiAccess a collection of open-source molecular design and structural biology tools on the Tamarind Bio platform, via its REST API or MCP server — no local GPUs required. Tamarind bundles popular open-source models for structure prediction (AlphaFold, Boltz, Chai, ESMFold), protein, binder, and de novo design (RFdiffusion, ProteinMPNN, BoltzGen), antibody and nanobody design and developability, protein-ligand docking (DiffDock, Autodock Vina), binding-affinity prediction, MSA generation, and molecuuncertainty-and-unitsk-dense-aiTrack physical units and propagate measurement uncertainty in scientific calculations using pint and uncertainties. Use for unit conversion and dimensional checking, GUM uncertainty budgets, Type A and Type B evaluation, coverage factors and expanded uncertainty, Monte Carlo propagation, significant-figure and plus-minus reporting, error propagation through curve fits, CODATA constants, auditing Python code for stripped units or broken uncertainty propagation, and order-of-magnitude plausibilitywaypoint-biok-dense-aiUse when working with Outpost Bio's open microbiome foundation models - the Waypoint checkpoints (Waypoint-6m, Waypoint-45m, Waypoint-170m), the Atlas pretraining corpus, the Compass eight-task benchmark, or the `waypoint` CLI from the `waypoint-bio` package. Covers embedding microbiome samples, fine-tuning on taxonomic abundance data, benchmarking a checkpoint on Compass, pretraining a GPT-2 model on taxonomic abundance profiles, and converting MetaPhlAn, Kraken2, QIIME 2, or MGnify abundance tofficial-document-writingkagurananaga专业的党政机关公文写作指南。当用户需要撰写、修改或审核党政机关公文（如请示、通知、函、总结、纪要等）时使用。提供GB/T 9704-2012格式规范指导、常用公文模板、语言规范建议和公文质量检查。适用于以下场景：(1) 撰写新公文，(2) 修改完善公文，(3) 检查公文格式规范，(4) 提供公文写作指导，(5) 审核公文质量。amapkaichen通过脚本直连高德 Web Service API 完成地理编码、逆地理编码、IP 定位、天气、路径规划、距离测量和 POI 查询。用户要求“高德/AMap 查询”“路线规划”“地理编码”“POI 搜索”或需要用命令行脚本调用高德 API 时使用。twitterapi-iokaitoinfraOfficial skill for twitterapi.io — query Twitter/X data (tweets, profiles, followers, advanced search, trends, spaces, communities, lists) and perform authenticated actions (post, reply, like, retweet, follow, DM) via the twitterapi.io REST API using a single `x-api-key` header — no OAuth. Use when the user needs to scrape, analyze, monitor, or automate X/Twitter without going through the official developer portal.video-lenskar2phiFetch a YouTube transcript and generate an executive summary, key points, and timestamped topic list as a polished HTML report. Activate on YouTube URLs or requests like "summarize this video", "what's this about", "give me the highlights", "TL;DR this", "digest this video", "watch this for me", "I watched this and want a breakdown", or "make notes on this talk". Supports non-English videos, language selection, and yt-dlp enrichment for chapters, video description, and richer metadata. Falls bactax-advisorkazukinagataThis skill should be used when the user asks tax-related questions, wants advice on deductions or tax savings, or needs expert guidance equivalent to a tax accountant (税理士) or life planner. Trigger phrases include: "税金について教えて", "控除は使える？", "確定申告の相談", "節税", "ふるさと納税の上限", "iDeCoの効果", "住宅ローン控除", "青色申告のメリット", "消費税はかかる？", "扶養に入れる？", "配偶者控除", "医療費控除", "法人成り", "経費になる？", "税率を教えて", "所得税の計算", "住民税", "社会保険料", "103万の壁", "130万の壁", "インボイス", "簡易課税", "税制改正", "開業届", "副業バレ", "白色申告", "税務調査", "特定支出控除", "予定納税", "中間納付"kernel-agent-browserkernelBest practices for using agent-browser with Kernel cloud browsers. Use when automating websites with agent-browser -p kernel, tuning stealth or proxy behavior, persisting profiles, handling iframes, discovering Kernel session IDs or live views, or cleaning up cloud sessions.kernel-clikernelUse the Kernel CLI to manage cloud browsers, apps, profiles, proxies, managed auth, API keys, projects, and organization limits. Use when installing or authenticating the CLI, looking up current command syntax, or choosing the right command group.academic-deep-researchkesslerioTransparent, rigorous research with full methodology — not a black-box API wrapper. Conducts exhaustive investigation through mandated 2-cycle research per theme, APA 7th citations, evidence hierarchy, and 3 user checkpoints. Self-contained using native OpenClaw tools (web_search, web_fetch, sessions_spawn). Use for literature reviews, competitive intelligence, or any research requiring academic rigor and reproducibility.frontend-design-ultimatekesslerioCreate distinctive, production-grade static sites with React, Tailwind CSS, and shadcn/ui — no mockups needed. Generates bold, memorable designs from plain text requirements with anti-AI-slop aesthetics, mobile-first responsive patterns, and single-file bundling. Use when building landing pages, marketing sites, portfolios, dashboards, or any static web UI. Supports both Vite (pure static) and Next.js (Vercel deploy) workflows.dart-best-practiceskevmooGeneral best practices for Dart development. Covers code style, effective Dart, and language features.dart-test-fundamentalskevmooCore concepts and best practices for `package:test`. Covers `test`, `group`, lifecycle methods (`setUp`, `tearDown`), and configuration (`dart_test.yaml`).primevuekindySetup and use PrimeVue UI component library in Vue/Vite projects with auto-import, theming, and component configuration. Use when working with PrimeVue components, setting up PrimeVue in a Vue project, configuring themes (Aura, Lara, etc.), or implementing auto-import for PrimeVue components.nano-bananakingbootoshiGenerates AI images using the nano-banana CLI (Gemini 3.1 Flash default, Pro available). Handles multi-resolution (512-4K), aspect ratios, reference images for style transfer, green screen workflow for transparent assets, cost tracking, and exact dimension control. Use when asked to "generate an image", "create a sprite", "make an asset", "generate artwork", or any image generation task for UI mockups, game assets, videos, or marketing materials.applykirkchenUse when implementing a Beat change — requires gherkin or proposal artifact to be done firstarchivekirkchenUse when a Beat change is complete (implemented, or distilled and verified) and ready to archive — not for verifying implementationdesignkirkchenUse when starting a Beat change to create spec artifacts — not for task breakdown, implementation, or explorationdistillkirkchenUse when extracting BDD specs from existing code — for adopting Beat in an established codebase or distilling a module into feature filesexplorekirkchenUse when thinking through ideas, investigating problems, or clarifying requirements — before or during a Beat changeplankirkchenUse when breaking down a Beat change spec into tasks — not for spec creation or implementationsetupkirkchenUse when initializing Beat or updating its config — not for editing config.yaml directly or non-Beat toolsverifykirkchenUse when validating implementation against spec artifacts before archive — not for design, planning, or implementationpr-reviewkirkchenUse when reviewing a PR/MR diff for security, logic, performance, cross-file impact, test coverage, or spec compliance findings. NOT for writing PR descriptions, design reviews requiring business judgment, implementation work, release notes, or deep CVE/supply-chain audits.self-reviewkirkchenUse when doing dev-stage self-review on the current branch before pushing or opening a PR — runs an auto-loop of codex review (cross-model, OpenAI) + per-finding fix + re-review until findings converge or stop conditions fire. Codex follows pr-review's multi-role methodology (security / staff-engineer / sdet / spec-auditor). Triggers — 'self review', 'self-review', '自己 review', '自我 review', 'cross-model review', 'pre-push review', 'review and fix my branch'. NOT for live PR review with sticky/instock-trade-journalkirkluokun按统一规则记录交易流水。按个股落 Markdown，同时写入 SQLite 便于统计与量化复盘。12306kirorabQuery China Railway 12306 for train schedules, remaining tickets, and station info. Use when user asks about train/高铁/火车 tickets, schedules, or availability within China.motel-debugkitlangtonDebug applications with motel, a local OpenTelemetry ingest and query server. Use when the user wants runtime-evidence debugging with traces or logs, wants temporary debug instrumentation that can be removed later, or needs a repo wired to send OTLP/HTTP telemetry to a local motel server. If the target repo uses Effect or @effect/*, also read references/effect.md.